Conferinţa ştiinţifică anuală "Cercetarea în biomedicină și sănătate: calitate, excelență și performanță", 2021: Recent submissions

  • Bioenergetic inhibitors – a new group of antituberculous drugs 
    Tărăburcă, Mihaela (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. One way of developing new anti-tuberculosis drugs are inhibitors of energy metabolism, which act on the electron transport chain and oxidative phosphorylation, affecting both growing and dormant bacilli. ...
  • Drug interactions and adverse reactions in HIV-positive patients 
    Vesiolîi, Sorina (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. The therapeutic regimen associates a complex antiretroviral treatment and other drugs in associated diseases that can generate a series of pharmacokinetic and pharmacodynamic interactions. Objective of the ...
  • The action of Taraxacum Officinale extracts on thiols content 
    Fulga, Ala (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Taraxacumofficinale F. H. Wigg (TO) represents an important source of phytosterols, triterpenes, phenolic compounds with different functions, antioxidative too. The high reactivity of thiol groups involves ...
  • Development of biosimilar growth hormon 
    Cazacu, Radu; Rusnac, Liliana; Valica, Vladimir; Scutari, Corina (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Recombinant human growth hormone (rhGH) has been in clinical use for more than 30 years. With the expiration of patent exclusivity for the first wave of rhGH products and other biopharmaceuticals, the opportunity ...
  • Complications of antibacterial drug therapy 
    Ciornoluțchii, Vera (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Antibacterial drugs are widely used worldwide. The demonstration of the particularities of the risks associated with their administration and the application of their prophylaxis measures determine the increase ...
  • Modifications of the erythrocytic antioxidant system in the administration of new coordinative compounds 
    Pantea, Valeriana; Gamaniuc, Marina; Popa, Veaceslav (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Currently, there is a growing interest in new local coordination compounds (CC), which demonstrated antitumor properties, but their influence on the erythrocyte antioxidant system has not studied. Objective ...
  • Comparative study of alkaloids in species of genus Galanthus from the Alexandru Ciubotaru National Botany Garden 
    Țărnă, Carmelia (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. In the local flora there are 3 species with different degrees of vulnerability from g. Galanthus. In order to restore the natural populations, the species were multiplied in vitro in the Plant Biotechnologies ...
  • Therapeutic management of the migraine 
    Morcov, Cristiana (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. The migraine is a chronic multifactorial pathology, characterized by recurrent headache attacks in subjects with genetic and biological predisposition, affecting 30% of the general population. Successful ...
  • Synergistic effect of obesity on the lymphatic system 
    Melinte, Mihaela (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. The lymphatic system is a component of the cardiovascular system, it plays an important role in fluid homeostasis, macromolecules transport, regulation, and modulation of the immune response, as well as in ...
  • Condition of paravertebral muscles in inginal hernias 
    Guzun, Gheorghe; Turchin, Radu; Vișnevschi, Sergiu (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. . Decreased tone of the anterolateral abdominal wall muscles, actually is considered the main etiological factor in the appearance of inguinal hernia. Taking into consideration that the spinal nerves have the ...
  • The role of chondrocyte apoptosis in the pathogenesis of osteoarthritis 
    Milicenco, Alexandru (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Osteoarthritis is characterized by degeneration of articular cartilage. There are several molecular factors of chondrocyte apoptosis that contribute to the degradation of cartilage in osteoarthritis, but do ...
  • Aspects regarding risk management in the process of circulation of medicines 
    Cheptanari-Bîrta, Nicoleta (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. The management, storage, release and use of pharmaceuticals are risky operations. Risk management in this field aims at the quality, monitoring, evaluation, verification, control, throughout the circulation ...
  • The importance of plasma amino acid profile in the diagnosis of inboorn errors of metabolism 
    Hlistun, Victoria; Efremov, Egor; Blăniță, Daniela; Boiciuc, Chiril; Ușurelu, Natalia (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Inborn errors of metabolism (IEM) make up a large group of disorders caused by an inherited defect of proteins that have enzymatic, carrier, receptor or structural roles. Early recognition and intervention ...
  • Genetic polymorphism of beta-adrenoblockers and efficiency in cardiovascular pathology 
    Bacinschi, Georgel (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. The genetic polymorphism of beta-1-adrenoreceptors and cytochrome P-450 enzymes may determine the efficacy and harmlessness of beta-adrenoblockers in the treatment of cardiovascular disease, hypertension and ...
  • Chemical study of three genotypes of Hyssopus officinalis l. cultivated in the Republic of Moldova 
    Benea, Anna; Pompuș, Irina; Ciobanu, Cristina; Ungureanu, Ion; Ciobanu, Nicolae; Cojocaru-Toma, Maria (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. H. officinalis L. - medicinal, culinary plant widespread in Europe and Asia. The main phenolic compounds are flavonoids and hydroxycinnamic acids, with carminative, tonic, antiseptic, expectorant and antitussive ...
  • Phapharmaceutical assistance in the management of COVID-19 infection 
    Chițan, Elena; Brumărel, Mihail (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Guaranteeing the right to health of the population can only be achieved by promoting the continuous and equitable insurance of the population with safe, effective and quality medicines, as well as promoting ...
  • The role of the pharmacist in the management of allergic rhinitis in the community pharmacy 
    Sîbii, Lucia; Adauji, Stela (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Allergic rhinitis is frequently ignored, underdiagnosed, misdiagnosed and mistreated, damaging health and inducing social and direct costs of treatment. A significant number of patients with allergic rhinitis ...
  • Evaluation of the antibacterial consumption in public medical and sanitary institutions in the R. of Moldova in the COVID-19 pandemic 
    Macari, Doina (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. Despite the fact that antibiotics do not treat or prevent viral infections like COVID-19, the results of behavioural insight research conducted in 9 countries and areas of the European Region showed antibiotic ...
  • Histological and immunohistochemical study of 2 cases of deep soft tissue leiomyoma 
    Cazacu, Eugeniu; Pretula, Ruslan; Mărițoi, Tatiana (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. The low incidence of deep soft tissue leiomyoma, the absence of signs and symptoms of onset in most cases are important problems in attempts to detect the disease early. Objective of the study. The aim of our ...
  • Determination of potassium orotate in mechanical mixture with spironolactone, potassium aspartate and magnesium by UV-Vis spectrophotometry 
    Mazur, Ecaterina; Uncu, Livia (Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova, 2021)
    Background. The UV-Vis spectrophotometry is used successfully in the analysis of fixed-dose combination (FDC). The determination of the active substances with the different chemical structures leads to difficulties in ...

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