MedEspera 2024: Recent submissions

  • Gestational diabetes mellitus and macrosomia: municipal clinical hospital ”Gheorghe Paladi” experience 
    Micinschi, Nadina; Catrinici, Rodica; Baxan, Alexandra (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Gestational diabetes mellitus (GDM) is a metabolic complication during pregnancy. It is defined by the development of glucose intolerance, primarily diagnosed in pregnancy. According to literature between ...
  • Congenital vascular malformations of the aortic arch as a risk factor for recurrent pneumonia in children - case report 
    Mîndru, Elena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Congenital heart disease (CHD) is one of the most common congenital structural disorders in childhood morbidity with a prevalence of 10 cases per 1000 live births, and is an important cause of childhood ...
  • Pharmacological approach to Wernicke-Korsakoff syndrome 
    Cernov, Ecaterina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Wernicke-Korsakoff Syndrome (WKS) represents, in 16-38% of cases, a clinical triad of confusion, ataxia and nystagmus. Conceptualized as two distinct syndromes, 85% of survivors of the untreated acute phase ...
  • Particularities of the action of the inhibitors of the renin-angiotensin-aldosterone system in men and women 
    Nicolenco, Nicoleta (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The renin-angiotensin-aldosterone system (RAAS) plays a significant role in cardiovascular pathology, including arterial hypertension (HTA). It has been demonstrated that endogenous sex hormones interact ...
  • Morphological and immunohistochemical features in the differential diagnosis of hydatiform mole 
    Rusnac, Ioana Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Hydatidiform mole is a pathological pregnancy that belongs to the gestational trophoblastic diseases group. During histomorphological lesion examination, differentiating between molar and non-molar lesions ...
  • How to better learn hypertensive disorders of pregnancy through simulation in Republic of Moldova 
    Budianu, Cătălina; Grajdean, Elena; Manic, Milena; Coșpormac, Mihaela; Cemortan, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The incidence of hypertensive disorders of pregnancy (HDP) has been reported up to 5-9%, with a significant rate of subsequent preeclampsia (15%), eclampsia (2%), and a high rate of maternal /fetal mortality ...
  • Role of fibroblasts and other non-fibroblastic stromal cells in sustaining the thyroid gland structure 
    Berbeci, Alexandrina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The thyroid gland is one of the most important endocrine organs that is responsible for producing hormones that regulate metabolism, growth, and development. Giving the primordial function of thyroid gland ...
  • Some aspects of optimization geriatric pharmacotherapy 
    Silnic, Tatiana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. One of the main tasks of the modern health system is ensuring an adequate quality of life for the elderly, whose share in the world is constantly increasing. At the same time, the changes associated with ...
  • Evaluation of phenolic compounds in ethanolic extract of Cichorium intybus L. by HPLC method 
    Ciorba, Alina; Cojocaru-Toma, Maria; Uncu, Livia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Cichorium intybus L (Chicory), of the Asteraceae family, is a perennial herbaceous plant with a long tradition of use and various pharmacological activity such as: antibacterial, antiinflammatory, analgesic, ...
  • Phytochemical analysis of Hyssopus officinalis L. from Republic of Moldova 
    Lupușor, Tatiana; Benea, Anna (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. H. officinalis wildly grows in southern Europe, Central Asia, Russia and Iran. This species is one of the important medicinal plants and is extensively cultivated in Spain, France and Italy. The aerial ...
  • Management of generalized anxiety disorders in primary medical care 
    Cîmpanu, Violina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Nowadays, anxiety disorders are some of the most common disorders. A multitude of people around the world suffer from various forms of anxiety, like phobias, panic attacks, post-traumatic stress or generalized ...
  • Retrospective study of borderline personality disorder diagnosed and hospitalized in clinical hospital of psychiatry 
    Sanduleac, Lidia; Coleva, Ecaterina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Over the past five years, there has been a marked escalation in the incidence of borderline personality disorder (BPD) cases within the Republic of Moldova. The clinical landscape of BPD is characterized ...
  • Risk factors for dementia in Alzheimer's disease 
    Tureac, Irina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Alzheimer's disease is a progressive disorder that triggers brain regression and cell death in the cerebral cortex. Dementia in Alzheimer's disease presents one of the most widespread causes, making up about ...
  • How mental retardation and autism symptoms are more pronounced in boys with fragile X syndrome due to lack of genetic compensation 
    Baudzei, Carina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Fragile X syndrome is a genetic disorder that is inherited through the X chromosome. It is caused by a mutation in the FMR1 gene, which is located on the X chromosome. When a male inherits an X chromosome ...
  • Neuropsychiatric symptoms in Parkinson's disease 
    Loghin, Ana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. BP is a major medical problem. According to World Health Organization (WHO) data, the number of cases of Parkinson's disease is increasing. By 2030, the prevalence of Parkinson's disease will exceed 9 million ...
  • Risk factors for vascular dementia 
    Toporeț, Valeria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Vascular dementia is a neurodegenerative disorder that occurs due to cerebrovascular disease and hypoperfusion. This can range from large vessel stroke to microvascular disease. The symptoms and presentation ...
  • Light therapy for seasonal affective disorder (SAD): a meta-analysis of efficacy 
    Thayyil, Ayisha (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Affective Disorder is a growing concern in mental health, and this study explores the effectiveness of light therapy. This meta-analysis delves into the efficacy of light therapy as a treatment for SAD. The ...
  • Side effects of benzodiazepine use 
    Buga, Ina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. BZDs are a class of psychoactive drugs known for their depressing effect on the central nervous system (CNS). Given the continuous increase in anxiety and sleep disorders over decades, BZDs remain the most ...
  • Psychotrauma in correlation with depression 
    Arnaut, Tatiana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The XXI century is a century of dynamic events. Constant technical evolution, fast pace of life, fierce competition leads to physical and mental exhaustion, which subsequently forms psychotrauma, which in ...
  • Lipid profile variations during pregnancy 
    Marian, Andriana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Variations in the maternal lipid profile during pregnancy are an absolutely normal phenomenon, this contributes to good fetal intrauterine development. Hyperlipidemia is appreciated more frequently starting ...

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