MedEspera 2024: Recent submissions

  • Gene therapy for adenosine deaminase severe combined immunodeficiency (ADA-SCID) 
    Bogdanov, Alan (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. About 1 in 500,000 people are born with severe combined immunodeficiency (SCID). The adenosine deaminase variant is a fatal inborn error of purine metabolism. Accumulation of adenosine and deoxyadenosine ...
  • New concepts of treatment of carpal tunnel syndrome 
    Lungu, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Carpal tunnel syndrome is the most common form of focal peripheral compressive mononeuropathy of the median nerve accompanied by pain, paresthesia, weakness along the nerve's path and represents approximately ...
  • Pharmacological approach to Wernicke-Korsakoff syndrome 
    Cernov, Ecaterina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Wernicke-Korsakoff Syndrome (WKS) represents, in 16-38% of cases, a clinical triad of confusion, ataxia and nystagmus. Conceptualized as two distinct syndromes, 85% of survivors of the untreated acute phase ...
  • Particularities of the action of the inhibitors of the renin-angiotensin-aldosterone system in men and women 
    Nicolenco, Nicoleta (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The renin-angiotensin-aldosterone system (RAAS) plays a significant role in cardiovascular pathology, including arterial hypertension (HTA). It has been demonstrated that endogenous sex hormones interact ...
  • Mechanisms of drug-induced nephrotoxicity 
    Iapara, Olga (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Drug-induced nephrotoxicity or drug-induced renal disease (DRID) is a common clinical problem. It has been reported that the incidence of drug-induced renal disease in adults can range from 14-26% to 66% ...
  • Drugs of choice in hypertensive emergency associated with acute aortic dissection 
    Prijilevschi, Cristina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Acute aortic dissection is a hypertensive emergency that requires an immediate reduction of blood pressure (BP) by administering intravenous drug therapy. Diligent control of BP is the most crucial in order ...
  • Immunological peculiarities and the specifics of the use of therapeutic ozone in women with the risk of infertility 
    Zagorneanu, Cezar; Petrov, Cristina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. A quite specific problem regarding sexual and reproductive health that nowadays’ society is facing is represented by infertility amongst young women. This condition can be caused by a myriad of pathologies, ...
  • The histological miracle of the circulatory system 
    Ustroi, Liudmila (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The cardiovascular or circulatory system is designed to ensure the survival of all cells in the body at all times and does this by maintaining the immediate chemical environment of each cell in the body at a ...
  • Hyssopus officinalis L. the source of diosmin as the therapeutic agent in different diseases 
    Golub, Alexandrina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The species Hyssopus officinalis L. is known over the years as a medicinal plant based on volatile oils. In the last 3 decades, scientific researchers have highlighted different classes of therapeutically ...
  • Some aspects of optimization geriatric pharmacotherapy 
    Silnic, Tatiana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. One of the main tasks of the modern health system is ensuring an adequate quality of life for the elderly, whose share in the world is constantly increasing. At the same time, the changes associated with ...
  • Phytochemical analysis of Hyssopus officinalis L. from Republic of Moldova 
    Lupușor, Tatiana; Benea, Anna (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. H. officinalis wildly grows in southern Europe, Central Asia, Russia and Iran. This species is one of the important medicinal plants and is extensively cultivated in Spain, France and Italy. The aerial ...
  • Knowledge, attitudes, and practices regarding hepatitis B and C among students at "Nicolae Testemițanu" State University of Medicine and Pharmacy 
    Călugăreanu, Valentin (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Viral hepatitis B and C represent significant global public health challenges with a profound impact on the population. Students at the "Nicolae Testemitanu" State University of Medicine and Pharmacy (USMF) ...
  • Legal instruments for the protection of children's rights against acts of violence 
    Suman, Lidia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Violence against children is still a widespread phenomenon in the Republic of Moldova, as only in 2020, 26% of girls and 35% of boys were subjected to physical violence by the age of 18. In the 2020-2021 ...
  • Nosocomial infections in surgical practice 
    Micșanschi, Dina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Nosocomial infections (NIs), also referred to as healthcare-associated infections (HAIs), are presently a major concern in surgical practice. The rates of nosocomial infections serve as a crucial indicator ...
  • Historical reflections on drinking water: hygienic and social significance 
    Curteanu, Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Drinking water has always been a vital resource for the survival and development of human societies. Historically, access to clean water has significantly influenced the health, culture, and social structures ...
  • Microbial resistance to antibiotics 
    Tabarcea, Corneliu (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The use of antibiotics (ABs) in the treatment of pathologies caused by microorganisms has saved many human lives, but subsequently, bacterial infections have again become a severe threat due to antimicrobial ...
  • Occupational stress for therapeutic and surgical doctors. Comparative study 
    Ciutac, Marius (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Occupational stress represents a significant problem for doctors in the therapeutic and surgical fields, having a profound impact on their mental health and the quality of the medical act. Occupational ...
  • In vitro biofilm formation by S. aureus isolated from oral infections and their association with antimicrobial resistance 
    Mamaliga, Mihaela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Staphylococcus aureus is an opportunistic pathogen most commonly involved in skin and soft tissue infections. It is part of the normal microflora of the nasopharynx, skin, eyes, intestines, and urogenital ...
  • Intercultural communication in the Francophone European Youth Community 
    Cristea, Daniel (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Intercultural communication remains an important necessity and a method of getting to know one another among French-speaking young people in the European community. Intercultural communication is at the ...
  • Measuring and evaluation – basic tools in public health 
    Rîmiș, Paola (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The problem of preservation of the health of the population is considered a top priority for public health, which requires the development of coordinated actions to improve the health and quality of life ...

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