MedEspera 2024: Recent submissions

  • Predisposing factors in the development of transverse malocclusions 
    Talmaci, Ana-Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Transverse malocclusions represent conditions that encompass a discrepancy in the alignment of teeth and maxillae in the transverse plane. Their etiology involves multiple aetiological factors that interact ...
  • Osteomyelitis of the lower jaw 
    Colioglo, Liudmila (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The problem of osteomyelitis has a long history. Despite certain successes in the fight against purulent infection, osteomyelitis of the jaws remains a pressing problem in modern medicine. This is due to the ...
  • Open bite morbidity in school-aged children 
    Bulmaga, Alina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The study of open bite is relevant due to the increase in the incidence of dentomaxillary anomalies in recent years caused by the complexity of functional disorders and orthodontic treatment difficulties. An ...
  • Relationship between visual impairment and eyelid ptosis 
    Ignatiev Vitalina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Eyelid ptosis develops in many patients as they age. The cause is mainly age-related changes in the skin and formation of fat hernias, the reason for which is weakening of the turgor of the eye muscle. Most ...
  • Single-visit treatment of acute pulpitis 
    Corbu Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Pulpitis represents the reactions and processes that occur in the dental pulp under the action of pathogens that act intensely on the tooth or that come into direct contact with the dental pulp. Following the ...
  • Critical decisions in coronary interventions: bypass vs. stent - a detailed analysis 
    Coicoiu, Vlad (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. In the context of cardiovascular interventions, coronary artery bypass grafting (CABG) and coronary stenting represent distinct approaches to address coronary artery disease and the choice between them ...
  • Metastatic mature teratoma association with azoospermia due to bilateral cryptorchidism and testicular benign teratoma: case report 
    Karabacak Ozcan Yasin; Valeanu Ion; Iurii Arian (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Azoospermia, the most severe type of male infertility, is caused by numerous untreatable testicular problems. Approximately 10% to 15% of all male infertile individuals suffer from azoospermia, which affects ...
  • The comparative study between endourological and minimally invasive treatment of reno-ureteral lithiasis 
    Agache Marinela; Corneliu Maximciuc (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Lithic urological obstruction is ranked 3rd among urological diseases worldwide, following renal infectious pathologies and prostate pathologies. At the national level, it is the most prevalent urological ...
  • The role of prostatic inflammatory pathologies on male fertility 
    Moroz Marina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Inflammation significantly impacts prostate health, contributing to issues like prostatitis. Triggered by infection, autoimmune response or other factors, it can compromise sperm quality or cause prostate ...
  • Treat-to-target strategy in the treatment of rheumatoid arthritis 
    Sufichaev, Simona (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Rheumatoid arthritis (RA) is a chronic autoimmune condition characterized by progressive joint inflammation and structural damage that frequently results in severe disability. Aim of study. The "Treat-to-Target" ...
  • Role of mineralocorticoid receptor pathway in the pathogenesis of diabetic retinopathy 
    Toncoglaz, Alexandra (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Diabetic retinopathy (DR) represents a major cause of irreversible blindness among the working-age population. Aldosterone has an important role in the pathogenesis of DR, through vascular regulation, oxidative ...
  • Key non-receptor tyrosine kinases in adaptive immunity 
    Osoianu, Inesa (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Non-receptor tyrosine kinases (NRTKs) are cytosolic enzymes, grouped together as a subclass of protein tyrosine kinases (TKs) due to their lack of an extracellular and transmembrane domain, unlike receptor ...
  • Hereditary angioedema with C1 inhibitor deficiency 
    Butucel, Ana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Hereditary angioedema (HAE) is a rare autosomal dominant disease with deficiency or/and dysfunction of C1 inhibitor, caused by mutations in the C1-INH gene. HAE is characterized by potentially life-threatening ...
  • Comorbidities in gout 
    Praștină, Alexandra (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Gout is a member of the microcrystalline arthritis group characterized by musculoskeletal involvement and is also associated with a high incidence of comorbidities. Serum urate concentrations in patients with ...
  • Molecular-genetic and environmental mechanisms of myopia 
    Moldovanu, Mirela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Myopia is a multifactorial pathology that causes the decrease or loss of vision, in most cases the elongation of the longitudinal axis of the eyeball is involved. From an etiological point of view, numerous ...
  • Expression of the inflammatory syndrome manifestations in patients with seronegative rheumatoid arthritis 
    Utocichina, Ana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Rheumatoid arthritis (RA), a systemic autoimmune disease that is predominantly affecting synovial joints through a progressive destructive process, is classified into 2 subgroups - seronegative (SNRA) and ...
  • Meningococcal infection: clinical-evolutionary particularities 
    Caramalac, Cristina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Meningococcal infection is an acute infectious disease caused by meningococcus, occurring with a variety of clinical manifestations - from asymptomatic carriage and nasopharyngitis to generalized forms (purulent ...
  • The bone in the elderly 
    Trofimov Cristian; Mazur-Nicorici Lucia; Stratulat Silvia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Bone remodeling is a complex phenomenon regulated by bone cells and enzymes implicated in bone metabolism. Aim of study. The aim of the study was to describe the processes involved in bone remodeling during ...
  • Basal cell carcinoma, clinical aspects 
    Rachieru, Valentina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Basal cell carcinoma (BCC) is a non-melanocytic skin cancer that originates from the basal cells of the epidermis. This condition is characterized by a continuously increasing incidence, attributed to the ...
  • Depression after cerebral vascular accident: frequency, risk factors and impact on quality of life 
    Timuș, Roman; Gavriluța, Diana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Post-stroke depression is one of the most common complications, affecting about one third from the survivors after a stroke. In combination with cognitive aggravation, post-stroke depression slows down the ...

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