MedEspera 2024: Recent submissions

  • Neurological impairment in systemic lupus erythematosus 
    Dubalaru, Daniela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. SLE is a multifactorial autoimmune disease of unknown etiology, which is characterized by a diverse multisystemic effect that appears as the result of certain imperfect immunoregulatory processes. Aim of ...
  • Molecular-genetic and environmental mechanisms of myopia 
    Moldovanu, Mirela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Myopia is a multifactorial pathology that causes the decrease or loss of vision, in most cases the elongation of the longitudinal axis of the eyeball is involved. From an etiological point of view, numerous ...
  • Expression of the inflammatory syndrome manifestations in patients with seronegative rheumatoid arthritis 
    Utocichina, Ana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Rheumatoid arthritis (RA), a systemic autoimmune disease that is predominantly affecting synovial joints through a progressive destructive process, is classified into 2 subgroups - seronegative (SNRA) and ...
  • Basal cell carcinoma, clinical aspects 
    Rachieru, Valentina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Basal cell carcinoma (BCC) is a non-melanocytic skin cancer that originates from the basal cells of the epidermis. This condition is characterized by a continuously increasing incidence, attributed to the ...
  • Medical and social patterns of pelvic inflammatory disease in the Republic of Moldova 
    Căldare, Arina; Grăjdean, Victor; Vicol, Adrian; Manic, Milena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Pelvic inflammatory disease (PID) represents a significant medical and social problem. It encompasses conditions such as endometritis, salpingitis, hydrosalpinx, pyosalpinx, and tubo-ovarian abscess. The ...
  • Diagnosis of fetal growth restriction 
    Iuțis, Vlada; Catrinici, Rodica (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The prevalence of intrauterine fetal growth restriction continues to rise with an increased risk of perinatal mortality and morbidity. Accurate recognition of Intrauterine Growth Restriction (IUGR) holds ...
  • Application of virtual reality (VR) in the planning and simulation of urgent neurosurgical interventions 
    Todica, Vladislav (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Emergency neurosurgery is required for acute cerebrovascular disorders, intracranial and spinal cord traumas, and pre-cerebral artery occlusion/stenosis. It requires immediate and accurate management. Virtual ...
  • Chorio-villous mesenchymal stromal dysplasia in the course of pregnancies 
    Grosu, Eugenia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Mesenchymal stromal dysplasia is a developmental anomaly of the placenta that is characterized microscopically by dilated stem villi with a myxoid or hydropic appearance, cisterna lacunae, and lack of ...
  • The role of predictive factors of hemorrhagic transformation in patients with ischemic stroke undergoing intravenous thrombolysis 
    Frimu, Anastasia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Intravenous thrombolysis (IT) is the standard intervention for patients with ischemic stroke that demonstrates a significant rate of reduction in mortality and disability. Hemorrhagic transformation (HT) after ...
  • Prospects for obtaining liposomes with standardized plant extract 
    Stahi, Cristina; Yaman, Abdin (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. In recent years, scientists have shown an increasing interest in incorporating biologically active compounds extracted from plants into nanoparticle delivery systems. Examples of such delivery systems include ...
  • Anti-cancer compounds in brassica vegetables 
    Ciurea, Laura (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Cancer is the main cause of mortality and morbidity worldwide. According to the World Cancer Research Fund an estimated 40% of all human cancers are related to diet. Although a large variety of therapeutic ...
  • Use of sodium-glucose cotransporter 2 inhibitors in heart failure 
    Ferdohleb, Alexandrina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Heart failure syndrome has been designated as a major clinical and public health problem. Ischemic cardiopathy, arterial hypertension, cardiomyopathies, myocarditis, pericarditis valvulopathies, arrhythmias, ...
  • Comparative analysis of the national and international legislative framework regarding the storage of medicinal products for human use 
    Golovei, Ina; Adauji, Stela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Globally, regulating and managing medicines is vital for public health. This presentation compares how the Republic of Moldova and the European Union handle the storage and preservation of medicines. It ...
  • Antibacterial activity of basil essential oil 
    Boguș, Dorin (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Basil essential oil has been demonstrated to possess various beneficial properties, including analgesic, anti-inflammatory, antibacterial, hepatoprotective, and immunomodulatory effects. The multifunctionality ...
  • Action of biopharmaceutical factors on drug bioavailability 
    Andronachi, Gabriela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. According to the Food and Drug Administration (FDA), bioavailability represents the amount of active substance released from a pharmaceutical form, absorbed into the bloodstream, and reaching the site of ...
  • Drug interactions and errors in the treatment of hypertension in the elderly 
    Diaconu, Ion (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Hypertension is a condition in which the systolic and diastolic pressures are increased above the permissible limit. According to the European Society of Hypertension, for people without diabetes, the values ...
  • Treatment of convulsive syndrome in pediatric patients 
    Bugaian, Valeria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Convulsive syndrome represents paroxysmal cerebral crises, related to excessive and hypersynchronous activity of cortical and subcortical neurons. This condition is marked by uncontrolled muscle contractions, ...
  • Liposome biopharmaceutic and nanoparticles in human body 
    Costea, Anastasia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The use of nanotechnology in medicine, and more specifically in drug delivery, is rapidly spreading. Numerous substances are currently being researched for drug delivery and, in particular, cancer therapy. Aim ...
  • Borderline personality disorder in children and adolescents 
    Tapu, Andreea (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Borderline personality disorder is one of the most common psychiatric diseases worldwide. The clinical features of the disorder vary a lot depending on age, onset, gender, social status, and other comorbidities. ...
  • Anorexia and bulimia nervosa 
    Tatarciuc, Vlada (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction: Eating disorders, which are mentally debilitating, life-threatening, and financially burdensome conditions, significantly compromise physical well-being and disrupt psychosocial functionality. Current ...

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