IRMS - Nicolae Testemitanu SUMPh: Recent submissions

  • The role of cardiac fibrosis in diastolic heart dysfunction 
    Semionov, Marius (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Cardiac diastolic dysfunction (DD) represents globally one of the main causes for congestive cardiac failure, occurring in 1/3 of reported cases. DD is most commonly a consequence of systemic arterial ...
  • The role of NO and H2S in circulatory homeostasis regulation and dysfunction 
    Eremia, Alexandru (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Modern concept corroborates vascular endothelium as a crucial pillar regarding the control of a lot of vascular derived functions in circulatory homeostasis, such as: basal vascular tone and blood pressure, ...
  • Pathogenesis of sexual dysfunction 
    Azar, Fadi (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. This text discusses the prevalence and impact of sexual dysfunction, including issues like erectile dysfunction, orgasmic disorders, delayed ejaculation, premature ejaculation, and sexual pain disorders. Aim ...
  • Morphopathology significance in detection and differential diagnosis of gastritis 
    Stoica, Tatiana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The term Gastritis in morphopathology is used to describe the inflammation of gastric mucosa. Ordinarily gastritis is associated with Helicobacter Pylori which is positive in 85 % of patients, other cases of ...
  • Endocrine changes and menstrual dysfunctions in adolescent girls with obesity 
    Solcanu, Gabriela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. In recent decades, there has been a significant increase in the obesity rate among adolescent girls. According to the specialized literature, obesity induces hormonal changes that have consequences on sexual ...
  • HPV status and associated precursor lesion in vulvar squamous cell carcinoma 
    Butnaru, Adelina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. There are distinctive precursor lesions related to vulvar squamous cell carcinoma (VSCC) that are associated with high-risk human papillomavirus (HPV) type 16,18 specifically vulvar intraepithelial neoplasia ...
  • Gestational diabetes mellitus and macrosomia: municipal clinical hospital ”Gheorghe Paladi” experience 
    Micinschi, Nadina; Catrinici, Rodica; Baxan, Alexandra (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Gestational diabetes mellitus (GDM) is a metabolic complication during pregnancy. It is defined by the development of glucose intolerance, primarily diagnosed in pregnancy. According to literature between ...
  • Congenital vascular malformations of the aortic arch as a risk factor for recurrent pneumonia in children - case report 
    Mîndru, Elena (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Congenital heart disease (CHD) is one of the most common congenital structural disorders in childhood morbidity with a prevalence of 10 cases per 1000 live births, and is an important cause of childhood ...
  • Interventions for the prevention of smoking among children and adolescents 
    Cojocari, Diana; Bujor, Dina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Smoking is one of the most accepted habits among children and adolescents. Young people who use e-cigarettes or 'vaping' and other alternative forms of smoking have a wrong view of the risks they present. Aim ...
  • Morphological and immunohistochemical features in the differential diagnosis of hydatiform mole 
    Rusnac, Ioana Maria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Hydatidiform mole is a pathological pregnancy that belongs to the gestational trophoblastic diseases group. During histomorphological lesion examination, differentiating between molar and non-molar lesions ...
  • Etiology and treatment of supraventricular arrhythmias in children 
    Razak, Rajana (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The irregular heartbeats that take place above the ventricles are known as supraventricular arrhythmias. This study aims to investigate the causes as well as available treatments of supraventricular arrhythmias ...
  • Gluten intolerance. Celiac disease 
    Volc, Renata (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Celiac disease (CD) is an immune-mediated inflammatory condition of the small intestine that occurs in genetically predisposed individuals when they are exposed to gluten (a plant-based protein component found ...
  • The influence of type 2 pregestational diabetes mellitus on the fetus 
    Surlaru, Valeria (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The prevalence of type 2 diabetes among women of reproductive age is increasing. According to the latest data from the International Diabetes Federation in 2019, one in six live births is affected by hyperglycemia ...
  • Mechanisms of action and metabolic effects of anticoagulants 
    Curelariu, Mădălina; Stratulat, Silvia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Anticoagulant drugs antagonize coagulation and are used to prevent or prolong the clotting time. Nowadays physicians from different fields possess a broad panel of multiple anticoagulants to meet a patient's ...
  • Decoding AMD: exploring lipofuscin accumulation and metabolomics insights 
    Platon, Angela (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Age-related macular degeneration (AMD) represents a multifactorial, degenerative pathology of the retina, with mechanisms that remain incompletely understood. Lipofuscin accumulation is believed to play a ...
  • Biochemical aspects of malabsorption syndromes 
    Burdeniuc, Ion (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Malabsorption affects millions of people worldwide. Prevalence of coeliac disease in the general population ranges from 0,5% to 2%, with an average of about 1%. At present over 100,000 people suffer from ...
  • The anatomical variability of the last three pairs of the intercostal arteries 
    Croitoru, Dan; Coșciug, Stanislav (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The intercostal arteries are of vital significance in the vascularisation of the intercostal musculature, fascia and the ribs. The last three pairs are involved in the blood supply of the antero-lateral ...
  • Variational aspects of the deep femoral artery 
    Nacu, Zinaida (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. The deep femoral artery (DFA), also known as the deep artery of the thigh, classically, originates from the lateral semi-circumference of the femoral artery (FA), in the distal direction, at a distance of ...
  • Estrogen therapy - metabolic and clinical consequences 
    Briciuc, Eugenia; Stratulat, Silvia (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Estrogen therapy has been a cornerstone in the treatment of various medical conditions, especially in menopausal management symptoms, preventing osteoporosis and addressing gynecological concerns. However, ...
  • Corpus callosum agenesis in morphoclinical aspect 
    Rotaraș, Arina (Instituţia Publică Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica Moldova, 2024)
    Introduction. Agenesis of the corpus callosum (ACC) is a congenital brain anomaly, characterized by the absence of commissural fibers connecting the two large hemispheres of the brain. This can be partial or total and can ...